Postoperative meningitis. [5,12] Yoshiharu had reported a case of The purpose of this unique research is to analyse postoperative meningitis rate after craniotomy, and to compare the clinical characteristics, treatment outcomes and mortality rates of postoperative meningitis that were caused by Acinetobacter spp. This is an observational, partially The optimal timing for postoperative steroid withdrawal remains unclear. Here, we report the case of a 76-year-old woman who presented with nausea, dizziness, and cerebral discomfort following meningioma resection surgery and sub … This retrospective observational study aimed to explore the risk factors for postoperative meningitis following resection of meningioma. S. 6,7 A high index of suspicion for meningitis is essential in patients who have the clinical triad of fever, neck stiffness, and disturbance in sen-sorium during the postoperative period. In clean neurosurgery, the rate of postoperative bacterial meningitis is low (1–2%). Post-traumatic meningitis refers to a meningeal infection causally related The goal of this study was to develop a diagnostic prediction rule for postoperative meningitis using a combination of clinical, laboratory, and CSF variables, as well as risk factors (RFs) for CNS infection. baumannii is well recognized and has been described by many doctors worldwide. A total of 937 patients older than 18 years who underwent meningioma resection at the Department of Neurosurgery Meningitis can occur immediately or after many years following otologic surgery, necessitating continual vigilance. Epub 2007 May 2 doi: 10. We aimed to Keywords: meningitis, otologic surgeries, postoperative complications, systematic review INTRODUCTION infectious etiologies such as medication and neoplasm. The clinical manifestations and CSF findings as- sociated with aseptic meningitis are very similar to those associated with postoperative bacterial meningi- tis, and the distinction between the 2 entities is cur- Introduction Post-neurosurgical meningitis (PNM) is a severe disease, asso-ciated with high mortality rates, severe neurological sequelae, prolongation of hospital stay and costs [1e3]. Keywords: Postoperative meningitis, Bacterial meningitis, Spine surgery, Complications, Case report Among these postoperative infections, we found that the proportion of gram-negative bacilli is increasing, and there are increasingly more reports of Enterobacteriaceae ventriculitis and meningitis. The utility of preoperative testing of MRSA/MSSA status and antibiotics for decolonization to prevent postoperative meningitis should be further investigated. pneumoniae is the leading causative agent for postoperative meningitis. or other possible causes. Inner ear malformations increase susceptibility to postoperative meningitis. Background Postoperative bacterial meningitis is a rare complication of spinal surgery and is considered to be a complication related to intraoperative incidental durotomy. 5 ± 2 days during the intervention period (P = . [12,14] Therefore, vancomycin in addition to either cefepime, ceftazidime, or meropenem is recommended as empirical antimicrobial therapy for adult patients with BM post-surgery. Among that, nosocomial bacterial meningitis, also named post-neurosurgical bacterial meningitis (PNBM), refers to a category of severe complications after the craniotomy, causing inevitable obstacles in the procedures of neurosurgery. Postoperative meningitis showed no adverse effect on the results of spinal surgery after follow-up for at least two years. Objectives Postoperative meningitis following endoscopic endonasal transsphenoi-dal surgery (TSS) is a critical outcome metric. 1086/518169. The objective of this study was to estimate the overall pooled prevalence of meningitis following EIS. These findings can help identify patients with meningioma in need of special intervention to prevent postoperative meningitis and can help surgeons preoperatively identify the risk of postoperative meningitis for meningioma. 5 and 8%. Postoperative meningitis, especially caused by Acinetobacter spp. Seventy-five episodes of postoperative meningitis (21 cases of bacterial meningitis and 54 cases of aseptic meningitis) were investigated. The prevalence of meningitis after EIS varies greatly in the literature. PMID: 17516398 Management of cerebrospinal fluid leaks involving the temporal bone: report on 92 Bacterial meningitis is confirmed after culture of an organism from a lumbar puncture cerebrospinal fluid (CSF) aspirate. [ 9 ] The use of devices for therapeutic drainage of cerebrospinal fluid (CSF) or for intracranial pressure monitoring, such as external ventricular drains (EVD), external spinal drains (ESD), and shunts, is associated with an Postoperative meningitis can be caused by staphylococci and aerobic Gram-negative bacilli (including P aeruginosa). The agent profile, clinical and biochemical differences in gram-negative and gram-positive meningitis, and the The diagnosis of PNM is difficult because, unlike community-acquired meningitis, symptoms are less specific; patients are ill at baseline and many neurosurgical conditions mimic meningitis and cause cerebrospinal fluid (CSF) abnormalities. The reported incidence of postoperative meningitis is quite variable (0. Post-neurosurgical meningitis is an inflammation of the coverings of the brain following cranial procedures like craniotomy, stereotactic biopsy, and stereotactic craniotomy or ventriculoperitoneal shunt placement. Due to the low incidence of postoperative meningitis, very few studies have reported this complication after spinal surgery. Conclusions Postoperative rates of meningitis after EEA surgery were not significantly changed based on MRSA/MSSA colonization status of the patient or preoperative decolonization. A high index of suspicion for meningitis is essential in patients who have the clinical triad of fever, neck stiffness and consciousness disturbance during the postoperative period. Zarrouk V, Vassor I, Bert F, Bouccara D, Kalamarides M, Bendersky N, Redondo A, Sterkers O, Fantin BClin Infect Dis 2007 Jun 15;44 (12):1555-9. Abstract We reviewed the records of 70 consecutive adult patients with meningitis after a neurosurgical procedure, to determine the characteristics that might help to distinguish a sterile postoperative chemical meningitis from bacterial infection. Oct 17, 2025 · For post-operative meningitis, immediate treatment with intravenous ceftriaxone 2g every 12 hours or cefotaxime 2g every 6 hours, plus vancomycin 15-20mg/kg Meningitis is a potential complication of elective intracranial surgery (EIS). Feb 20, 2017 · Post-neurosurgical meningitis occurs after craniectomy, craniotomy or following the insertion of internal or external ventricular and lumbar catheters. It aims to do so through a systematic review CONTENTS General approach to neuroworsening after cranial surgery General postoperative management considerations Hemodynamics Seizure prophylaxis Analgesia & sedation Nausea and vomiting Fever Sodium abnormalities DVT prophylaxis General complications Intracranial hemorrhage Cerebral infarction Seizure Cerebral edema CSF leak Hydrocephalus Infectious complications Tension pneumocephalus Post-traumatic meningitis is a dreadful condition that presents additional challenges, in terms of both diagnosis and management, when compared with community-acquired cases. Meningitis is a potential complication of elective intracranial surgery (EIS). The purpose of this study was to report the clinical features, laboratory evaluations, treatment course and prognosis of 21 patients with post spinal surgery meningitis. It has been claimed that some cases of aseptic meningitis are due to a postoperative inflammatory reaction and may be treated with large doses of cortico- steroids [4], but the prevailing attitude is to give an empirical conibination of antibiotics against a possible Aim: To determine the microbiological etiology in critically ill neurosurgical patients with nosocomial meningitis (NM) and to show the impact of Gram-negative rods and the differences between patient characteristics and the clinical and prognostic measures in Gram-negative and Gram-positive meningitis. Post-traumatic meningitis refers to a meningeal infection causally related Post-traumatic meningitis is a dreadful condition that presents additional challenges, in terms of both diagnosis and management, when compared with community-acquired cases. Background: Post-operative nosocomial meningitis is a critical complication that develops in patients after neurosurgical interventions and operations. The panel represented pediatric and adult specialists in the field of infectious diseases and represented other organizations whose members care for patients with healthcare Objective This study aims to estimate the rate of postoperative meningitis (both immediate and long-term) in patients following cochlear implants (CIs). The clinical data of 62 adult patients who suffered post-neurosurgical nosocomial bacterial meningitis, retrospectively collected over a 16-year perio… Meningitis remains one of the most dreaded complications of neurosurgical procedures and is common in patients with preexisting infection. Central nervous system infections are recognized as a serious complication in patients, particularly in those with external ventricular drains. Pivotal CSF findings for diagnosis of PNM are the CSF glucose, CSF lactate and Gram stain. Evaluation of the management of postoperative aseptic meningitis. 10 Moreover, postoperative meningitis was associated with a prolonged hospital stay. In order to better define the pathogenic role of cerebrospinal fluid (CSF) drainage catheters in postoperative patients, we comparatively analyze the clinical course of device and non-device-related meningitis. Methods We conducted a retrospective analysis encompassing all patients who underwent glioma surgery involving craniotomy at Turku Objective To examine the risk of postoperative meningitis following expanded endoscopic endonasal skull base (EESB) surgery. The spinal fluid profiles in bacterial and chemical meningitis are similar. 8,9 Causative agents can spread intracranially through the Otologic surgeries are procedures of the outer, middle, middle and inner ear, directly to the meninges, or inner ear, and lateral skull base to address a range of hematogenously. MethodsA total of 937 patients older than 18 years w The meningitis caused by A. Identifying the risk factors associated with postoperative meningitis The Infectious Diseases Society of America (IDSA) Standards and Practice Guidelines Committee collaborated with partner organizations to convene a panel of 10 experts on healthcare-associated ventriculitis and meningitis. Setting A systematic analysis of publications identified through searches of the electronic databases from Embase (1980–July ObjectiveThis retrospective observational study aimed to explore the risk factors for postoperative meningitis following resection of meningioma. Chemical or aseptic meningitis is diagnosed with symptoms similar to bacterial meningitis but with a negative CSF culture. , and its inappropriate empirical treatment are associated with high mortality. This study aimed to determine the risk factors predisposing patients to PNM following surgery for low- and high-grade gliomas. Postoperative meningitis is associated with increase in the hospital stay and also increase in total cost of illness. Postoperative bacterial meningitis is a rare complication following spine surgery, but it can sometimes lead to devastating outcomes with long-term sequelae. This article aims to (1) present a patient with recurrent craniopharyngioma and multiple postoperative episodes of aseptic meningitis and (2) discuss the diagnosis and management of aseptic meningitis. Patients and Methods: Data were collected for 65 patients who were diagnosed as having nosocomial meningitis after neurosurgery. MSSA and CONS are the most common pathogens. Unlike community-acquired meningitis, mortality from postoperative meningitis is very unusual. 001). Most of case reports about the meningitis were associated with external ventricular drainage (EVD), cerebrospinal fluid (CSF) leaking, or head trauma [4 - 6]. Design Case report and literature review. Postoperative central nervous system infections (PCNSIs), including meningitis, cerebral abscesses, and implant-associated infections, represent critical complications following neurosurgical procedures. Postoperative meningitis is a rare complication after spinal lumbar surgery. Meningitis is one of the most severe complications in neurosurgery, particularly with transsphenoidal procedures, due to the potential for bacterial contamination from the nasal or sinus cavities. Abstract Background: Post-operative nosocomial meningitis is a critical complication that develops in patients after neurosurgical interventions and operations. Very few high-quality, randomized controlled trials of PNM management have been conducted, so diagnostic and therapeutic approaches are largely based on low-quality evidence and personal experience. Traditionally, patients with post-operative fever and increase of white blood cells following cerebral surgery are treated with the procedures in the treatment of bacterial meningitis. Background Post-neurosurgical meningitis (PNM) constitutes a grave complication associated with substantial morbidity and mortality. This study investigates the associa-tion between early postoperative corticosteroid withdrawal and outcomes following malignant glioma craniotomy. These infections pose significant risks to patient outcomes due to delayed diagnosis, escalating … Yang and colleagues retrospectively identified 31 patients with brain abscesses after neurosurgical procedures and found gram-negative bacilli and polymicrobial infections to be the most frequent pathogens isolated. Meta-analyses of proportions were Aseptic meningitis com- prises 60%-75% of all cases of postoperative menin- gitis. The overall incidence of dural tear ranges from 0. Here we reported five cases of PABM in the same neurosurgical intensive care Unit. Methods A retrospective cohort analysis was conducted using the TriNetX database. Patients with aseptic meningitis received antibiotic treatment for a mean ± standard deviation duration of 11 ± 5 days during the control period and 3. 15 Gram-negative bacilli are also the most common cause of postoperative meningitis and account for 29% to 38% of nosocomial The reported inci-dence, according to most literature, of postoperative menin-gitis is quite variable between 0. Gram-negative organisms are the most common causative pathogens of postoperative meningitis. A delay in diagnosis or treatment can Stopping antibiotic treatment after 3 days is effective and safe for patients with postoperative meningitis whose cerebrospinal fluid culture results are negative. The objective of this study was to estimate the overall pooled prevalence of meningitis following Jun 11, 2025 · Meningitis can occur immediately or after many years following otologic surgery, necessitating continual vigilance. Four databases (PubMed, Scopus, Web of Science, and Embase) were searched to identify relevant studies. 3% to 13% depending on the type and site of surgery [4]. Importantly, this complication is associated with an increased risk of postoperative meningitis, highlighting the clinical significance of early recognition and management of durotomies to prevent potential postoperative meningitis [4]. The diagnosis of PNM is difficult because, unlike community-acquired meningitis, symptoms are less specific; patients are ill at baseline and many neurosurgical conditions mimic meningitis and cause cerebrospinal fluid (CSF) abnormalities. Most post-operative infections after brain tumor surgery are diagnosed within a month of index surgery. The infection recurrence and readmission rate among these patients is relatively high at 35%, and is even greater in the presence of titanium mesh (50%). Conclusion. Some physicians even propose the treatment of meningitis with antibiotics regardless the aseptic meningitis and bacterial meningitis. Sep 1, 2017 · Post-neurosurgical meningitis occurs after craniectomy, craniotomy or following the insertion of internal or external ventricular and lumbar catheters. 5 to 8%). Postoperative meningitis is a rare but serious complication of neurosurgery. . This complex case required multiple surgical procedures to achieve a complete resolution. We present a case of a patient who experienced bacterial meningitis following endoscopic surgical intervention for lumbar disc herniation. 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